Genetics

Genetics is the study of hereditary and genetic factors and their implication in the development of different disease like cancer.

Mutation (alteration) of genes involved in the control of cell cycle and growth is a cornerstone in the development of cancer. The majority of mutations causing cancer are acquired following the exposure to certain mutagene (like smoking). A small proportion of these gene mutations are inherited and are known to pass from generation to the next one. Accumulation of DNA changes over time disrupt the normal cell regulation and cells divide out of control and eventually turn into a malignant one.

Basic genetic information needed to understand cancer biology and its treatment include:

The nucleus and nucleic acids.

Chromosomes.

DNA and RNA structures.

Genes: structure and expression.

The flow of genetic information.

The cell cycle.

Apoptosis

Tumor supressor genes

Read about:

 Monoclonal antibodies (MABs)
 

3- Cancer Immunotherapy and vaccines
• Preventive vaccines
• Therapeutic vaccines

4- Anti-Angiogenesis
 

5- Hormonal therapies: Most commonly used in the treatment of breast and prostate cancer.
 

6- Differentiating agents

7- Gene therapy drugs