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Gene expression and flow of genetic
information
The flow of the genetic
information:
The flow of genetic information
occurs through the process of transcription and translation.
Transcription is the
transfer of the genetic information from DNA into RNA by the aid
of an enzyme known as
polymerase. DNA → RNA.
Translation is the
transfer of the genetic information carried by the RNA into
protein. - RNA → Protein.
Worth noting that some viruses
transfer the genetic information from DNA into RNA. This is the
by the aid of an enzyme known as reverse transcriptase.
Transcription
In order to translate the
genetic code into a protein product or a cell structure, the
genetic code is first read and copied into another nucleic acid
known as RNA. The process is known as transcription. RNA or
ribonucleic acid is similar in structure to DNA except for two
main differences; RNA nucleotides contain ribose sugars while
DNA contains deoxyribose and RNA bases contain uracil instead of
thymine present in DNA.
Translation:
The transformation of the information encoded
in the nucleotides of mRNA into amino acid sequences that
constitute a specific protein structure is known as the process
of translation. Translation takes place in the cytoplasm when
the m RNA is transferred from the nucleus into the cytoplasm.
In translation, ribosomes decode the messenger RNA (mRNA)
genetic code to produce a specific polypeptide chain with the
aid of another RNA known as transfer t-RNA.
Protein synthesis:
-
Initiation: the recognition of the
initiating codon of the mRNA and the transfer of a
corresponding amino acid by specific tRNA to the small
ribosome subunit.
-
Elongation: the extension of the amino
acid chain by the transfer of the subsequent amino acids to
the proper ribosome site.
Termination: when the ribosome reaches
the termination codon of the mRNA. |